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Margaret Porter Scott

Margaret Porter Scott

Genentech, Inc - / United States
Medical and Health Sciences / Pharmacy & Pharmaceutical Sciences
AD Scientific Index ID: 4380741
person_outline Margaret Porter Scott's MOST POPULAR ARTICLES
1-) Selective killing of mixed lineage leukemia cells by a potent small-molecule DOT1L inhibitor Cancer cell 20 (1), 53-65, 2011
2-) A selective inhibitor of EZH2 blocks H3K27 methylation and kills mutant lymphoma cells Nature chemical biology 8 (11), 890-896, 2012
3-) Durable tumor regression in genetically altered malignant rhabdoid tumors by inhibition of methyltransferase EZH2 Proceedings of the National Academy of Sciences 110 (19), 7922-7927, 2013
4-) Coordinated activities of wild-type plus mutant EZH2 drive tumor-associated hypertrimethylation of lysine 27 on histone H3 (H3K27) in human B-cell lymphomas Proceedings of the National Academy of Sciences 107 (49), 20980-20985, 2010
5-) Potent inhibition of DOT1L as treatment of MLL-fusion leukemia Blood, The Journal of the American Society of Hematology 122 (6), 1017-1025, 2013