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Alexander Metz

Alexander Metz

Philipps Universität Marburg - Marburg / Germany
Medical and Health Sciences / Pharmacy & Pharmaceutical Sciences
AD Scientific Index ID: 1762852
Philipps University of Marburg
person_outline Alexander Metz's MOST POPULAR ARTICLES
1-) Hot spots and transient pockets: predicting the determinants of small-molecule binding to a protein–protein interface Journal of chemical information and modeling 52 (1), 120-133, 2012
2-) Six biophysical screening methods miss a large proportion of crystallographically discovered fragment hits: a case study ACS chemical biology 11 (6), 1693-1701, 2016
3-) One question, multiple answers: biochemical and biophysical screening methods retrieve deviating fragment hit lists ChemMedChem 10 (9), 1511-1521, 2015
4-) Modulating protein-protein interactions: from structural determinants of binding to druggability prediction to application Current pharmaceutical design 18 (30), 4630-4647, 2012
5-) Soaking suggests “alternative facts”: Only co-crystallization discloses major ligand-induced interface rearrangements of a homodimeric tRNA-binding protein indicating a novel … PLoS One 12 (4), e0175723, 2017